Research Summary
Platform technologies for genome design and cell construction
- Development of practical synthetic biology technologies for smart genetic circuit and genome synthesis 
- Development of DNA design software for high-accuracy DNA assembly 
- Development of artificial genome synthesis technology through genome design and modular assembly 
- Development of web-based Partbank database and standardization of bio-parts for biofoundry 
Development of high-throughtput technology
- Development of molecular evolution technologies for industrially applicable enzyme engineering 
- Development of high-speed and mass-volume biofoundry technologies to cope with climate change issues emerging as new threats 
CRISPR technology based biomedical and industrial applications
- Programmed probiotics with genetic circuits for diagnostics and therapeutics of inflammatory bowel disease 
- Establishment and applications of CRISPR technology for metabolic engineering 
- Development of therapeutic protein secretion system in bacteroides 
In responding to climate change and global warming
- Development of synthetic consortium of methanotrophs and heterotrophs to produce C4-chemicals from methane by mimicking the natural methane ecosystem 
- Development of CRISPR system for engineering methanotroph and partner microbe 
- Discovery of biological resources degrading PET using genetically encoded biosensors 
- Discovery and characterization of novel plastic degrading strains and enzymes 
- Mass production of biodegradable plastic monomers using acid-tolerant microorganisms 




